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Ion Mobility-Mass Spectrometry Analysis of Crosslinked Intact Multiprotein Complexes: Enhanced Gas-phase Stabilities and Altered Dissociation Pathways

Analysis of protein complexes by ion mobility-mass spectrometry is a valuable method for the rapid assessment of complex composition, binding stoichiometries, and structures. However, capturing labile, unknown protein assemblies directly from cells remains a challenge for the technology. Furthermore...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Samulak, Billy M., Niu, Shuai, Andrews, Philip C., Ruotolo, Brandon T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164941/
https://ncbi.nlm.nih.gov/pubmed/27078797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00518
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