Integrating Ion Mobility Mass Spectrometry with Molecular Modelling to Determine the Architecture of Multiprotein Complexes

Current challenges in the field of structural genomics point to the need for new tools and technologies for obtaining structures of macromolecular protein complexes. Here, we present an integrative computational method that uses molecular modelling, ion mobility-mass spectrometry (IM-MS) and incompl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Politis, Argyris, Park, Ah Young, Hyung, Suk-Joon, Barsky, Daniel, Ruotolo, Brandon T., Robinson, Carol V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919415/
https://ncbi.nlm.nih.gov/pubmed/20711472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012080
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