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Integrating Ion Mobility Mass Spectrometry with Molecular Modelling to Determine the Architecture of Multiprotein Complexes

Current challenges in the field of structural genomics point to the need for new tools and technologies for obtaining structures of macromolecular protein complexes. Here, we present an integrative computational method that uses molecular modelling, ion mobility-mass spectrometry (IM-MS) and incompl...

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Bibliografiska uppgifter
Huvudupphovsmän: Politis, Argyris, Park, Ah Young, Hyung, Suk-Joon, Barsky, Daniel, Ruotolo, Brandon T., Robinson, Carol V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919415/
https://ncbi.nlm.nih.gov/pubmed/20711472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012080
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