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GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation
Ubiquitin mediated proteolysis is required for transition from one cell cycle phase to another. For instance, the mitosis inhibitor Wee1 is targeted for degradation during S phase and G2 to allow mitotic entry. Wee1 is an essential tyrosine kinase required for the G2/M transition and S-phase progres...
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| 出版年: | Cell Cycle |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353296/ https://ncbi.nlm.nih.gov/pubmed/25616418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.974439 |
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