Nalaganje...
Hnf1b controls pancreas morphogenesis and the generation of Ngn3(+) endocrine progenitors
Heterozygous mutations in the human HNF1B gene are associated with maturity-onset diabetes of the young type 5 (MODY5) and pancreas hypoplasia. In mouse, Hnf1b heterozygous mutants do not exhibit any phenotype, whereas the homozygous deletion in the entire epiblast leads to pancreas agenesis associa...
Shranjeno v:
| izdano v: | Development |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Company of Biologists
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352981/ https://ncbi.nlm.nih.gov/pubmed/25715395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.110759 |
| Oznake: |
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