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The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1(+) progenitors and Ngn3(+) endocrine precursors
Cell division and cell differentiation are intricately regulated processes vital to organ development. Cyclin-dependent kinases (Cdks) are master regulators of the cell cycle that orchestrate the cell division and differentiation programs. Cdk1 is essential to drive cell division and is required for...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082297/ https://ncbi.nlm.nih.gov/pubmed/21490060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.061481 |
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