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The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1(+) progenitors and Ngn3(+) endocrine precursors

Cell division and cell differentiation are intricately regulated processes vital to organ development. Cyclin-dependent kinases (Cdks) are master regulators of the cell cycle that orchestrate the cell division and differentiation programs. Cdk1 is essential to drive cell division and is required for...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, So Yoon, Rane, Sushil G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Company of Biologists 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082297/
https://ncbi.nlm.nih.gov/pubmed/21490060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.061481
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