Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish

BACKGROUND: Insulin-producing beta cells emerge during pancreas development in two sequential waves. Recently described later-forming beta cells in zebrafish show high similarity to second wave mammalian beta cells in developmental capacity. Loss-of-function studies in mouse and zebrafish demonstrat...

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Bibliographic Details
Main Authors: Kimmel, Robin A, Onder, Lucas, Wilfinger, Armin, Ellertsdottir, Elin, Meyer, Dirk
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215967/
https://ncbi.nlm.nih.gov/pubmed/22034951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-9-75
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