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RB regulates pancreas development by stabilizing Pdx1
RB is a key substrate of Cdks and an important regulator of the mammalian cell cycle. RB either represses E2Fs that promote cell proliferation or enhances the activity of cell-specific factors that promote differentiation, although the mechanism that facilitates this dual interaction is unclear. Her...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102287/ https://ncbi.nlm.nih.gov/pubmed/21399612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.57 |
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