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Lack of TCF2/vHNF1 in mice leads to pancreas agenesis

Heterozygous mutations in the human POU-homeobox TCF2 (vHNF1, HNF1β) gene are associated with maturity-onset diabetes of the young, type 5, and abnormal urogenital tract development. Recently, pancreas atrophies have been reported in several maturity-onset diabetes of the young type 5 patients, sugg...

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Bibliografiska uppgifter
Huvudupphovsmän: Haumaitre, C., Barbacci, E., Jenny, M., Ott, M. O., Gradwohl, G., Cereghini, S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC547822/
https://ncbi.nlm.nih.gov/pubmed/15668393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405776102
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