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Sox9(+) ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

One major unresolved question in the field of pancreas biology is whether ductal cells have the ability to generate insulin-producing β-cells. Conclusive examination of this question has been limited by the lack of appropriate tools to efficiently and specifically label ductal cells in vivo. We gene...

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Detalhes bibliográficos
Main Authors: Kopp, Janel L., Dubois, Claire L., Schaffer, Ashleigh E., Hao, Ergeng, Shih, Hung Ping, Seymour, Philip A., Ma, Jenny, Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026412/
https://ncbi.nlm.nih.gov/pubmed/21266405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.056499
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