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Sox9(+) ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

One major unresolved question in the field of pancreas biology is whether ductal cells have the ability to generate insulin-producing β-cells. Conclusive examination of this question has been limited by the lack of appropriate tools to efficiently and specifically label ductal cells in vivo. We gene...

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Autors principals: Kopp, Janel L., Dubois, Claire L., Schaffer, Ashleigh E., Hao, Ergeng, Shih, Hung Ping, Seymour, Philip A., Ma, Jenny, Sander, Maike
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026412/
https://ncbi.nlm.nih.gov/pubmed/21266405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.056499
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