ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis

Increases in circulating glucagon during fasting maintain glucose balance by stimulating hepatic gluconeogenesis. Acute ethanol intoxication promotes fasting hypoglycemia through an increase in hepatic NADH, which inhibits hepatic gluconeogenesis by reducing the conversion of lactate to pyruvate. He...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Tsai, Wen-Wei, Matsumura, Shigenobu, Liu, Weiyi, Phillips, Naomi G., Sonntag, Tim, Hao, Ergeng, Lee, Soon, Hai, Tsonwin, Montminy, Marc
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352786/
https://ncbi.nlm.nih.gov/pubmed/25730876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424641112
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