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14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs)
The salt-inducible kinase (SIK) family regulates cellular gene expression via the phosphorylation of cAMP-responsive transcriptional coactivators (CRTCs) and class IIA histone deacetylases (HDACs), which are sequestered in the cytoplasm by phosphorylation-dependent 14-3-3 interactions. SIK activity...
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| Published in: | FEBS J |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5799007/ https://ncbi.nlm.nih.gov/pubmed/29211348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14351 |
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