Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members

The second messenger cAMP stimulates cellular gene expression via the PKA-mediated phosphorylation of the transcription factor CREB and through dephosphorylation of the cAMP-responsive transcriptional coactivators (CRTCs). Under basal conditions, CRTCs are phosphorylated by members of the AMPK famil...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Sonntag, Tim, Moresco, James J., Vaughan, Joan M., Matsumura, Shigenobu, Yates, John R., Montminy, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325614/
https://ncbi.nlm.nih.gov/pubmed/28235073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173013
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