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Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members

The second messenger cAMP stimulates cellular gene expression via the PKA-mediated phosphorylation of the transcription factor CREB and through dephosphorylation of the cAMP-responsive transcriptional coactivators (CRTCs). Under basal conditions, CRTCs are phosphorylated by members of the AMPK famil...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sonntag, Tim, Moresco, James J., Vaughan, Joan M., Matsumura, Shigenobu, Yates, John R., Montminy, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325614/
https://ncbi.nlm.nih.gov/pubmed/28235073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173013
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