Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members

The second messenger cAMP stimulates cellular gene expression via the PKA-mediated phosphorylation of the transcription factor CREB and through dephosphorylation of the cAMP-responsive transcriptional coactivators (CRTCs). Under basal conditions, CRTCs are phosphorylated by members of the AMPK famil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Sonntag, Tim, Moresco, James J., Vaughan, Joan M., Matsumura, Shigenobu, Yates, John R., Montminy, Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325614/
https://ncbi.nlm.nih.gov/pubmed/28235073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173013
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