ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis

Increases in circulating glucagon during fasting maintain glucose balance by stimulating hepatic gluconeogenesis. Acute ethanol intoxication promotes fasting hypoglycemia through an increase in hepatic NADH, which inhibits hepatic gluconeogenesis by reducing the conversion of lactate to pyruvate. He...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tsai, Wen-Wei, Matsumura, Shigenobu, Liu, Weiyi, Phillips, Naomi G., Sonntag, Tim, Hao, Ergeng, Lee, Soon, Hai, Tsonwin, Montminy, Marc
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352786/
https://ncbi.nlm.nih.gov/pubmed/25730876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424641112
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