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Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells

Wnt antagonism has been linked to glaucoma and intraocular pressure regulation, as has increased stiffness of human trabecular meshwork (HTM) tissue. We have shown culturing HTM cells on substrates that mimic the elevated stiffness of glaucomatous tissue leads to elevated expression of the Wnt antag...

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Detaylı Bibliyografya
Yayımlandı:Exp Eye Res
Asıl Yazarlar: Morgan, Joshua T., Raghunathan, Vijay Krishna, Chang, Yow-Ren, Murphy, Christopher J., Russell, Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352377/
https://ncbi.nlm.nih.gov/pubmed/25639201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.01.025
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