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Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells

Wnt antagonism has been linked to glaucoma and intraocular pressure regulation, as has increased stiffness of human trabecular meshwork (HTM) tissue. We have shown culturing HTM cells on substrates that mimic the elevated stiffness of glaucomatous tissue leads to elevated expression of the Wnt antag...

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Pubblicato in:Exp Eye Res
Autori principali: Morgan, Joshua T., Raghunathan, Vijay Krishna, Chang, Yow-Ren, Murphy, Christopher J., Russell, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352377/
https://ncbi.nlm.nih.gov/pubmed/25639201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.01.025
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