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Transforming Growth Factor Beta 3 Modifies Mechanics and Composition of Extracellular Matrix Deposited by Human Trabecular Meshwork Cells

Pseudoexfoliation syndrome is a systemic disorder of the extracellular matrix (ECM) with ocular manifestations in the form of chronic open angle glaucoma. Elevated levels of TGFβ3 in the aqueous humor of individuals with pseudoexfoliation glaucoma (PEX) have been reported. The influence of TGFβ3 on...

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Vydáno v:ACS Biomater Sci Eng
Hlavní autoři: Raghunathan, Vijay Krishna, Morgan, Joshua T., Chang, Yow-Ren, Weber, Darren, Phinney, Brett, Murphy, Christopher J, Russell, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419775/
https://ncbi.nlm.nih.gov/pubmed/30882039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ab500060r
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