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Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells

Wnt antagonism has been linked to glaucoma and intraocular pressure regulation, as has increased stiffness of human trabecular meshwork (HTM) tissue. We have shown culturing HTM cells on substrates that mimic the elevated stiffness of glaucomatous tissue leads to elevated expression of the Wnt antag...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Morgan, Joshua T., Raghunathan, Vijay Krishna, Chang, Yow-Ren, Murphy, Christopher J., Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352377/
https://ncbi.nlm.nih.gov/pubmed/25639201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.01.025
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