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Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype

PURPOSE: Wnt is a spatiotemporally regulated signaling pathway whose inhibition is associated with glaucoma, elevated intraocular pressure (IOP), and cell stiffening. Whether such changes are permanent or may be reversed is unclear. Here, we determine if activation of Wnt pathway after inhibition re...

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書目詳細資料
發表在:Invest Ophthalmol Vis Sci
Main Authors: Dhamodaran, Kamesh, Baidouri, Hasna, Sandoval, Lyndsey, Raghunathan, VijayKrishna
格式: Artigo
語言:Inglês
出版: The Association for Research in Vision and Ophthalmology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415288/
https://ncbi.nlm.nih.gov/pubmed/32539133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.30
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