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Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype

PURPOSE: Wnt is a spatiotemporally regulated signaling pathway whose inhibition is associated with glaucoma, elevated intraocular pressure (IOP), and cell stiffening. Whether such changes are permanent or may be reversed is unclear. Here, we determine if activation of Wnt pathway after inhibition re...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Dhamodaran, Kamesh, Baidouri, Hasna, Sandoval, Lyndsey, Raghunathan, VijayKrishna
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415288/
https://ncbi.nlm.nih.gov/pubmed/32539133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.30
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