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Lysophosphatidic Acid and IL-6 Trans-signaling Interact via YAP/TAZ and STAT3 Signaling Pathways in Human Trabecular Meshwork Cells

PURPOSE: Lysophosphatidic acid (LPA) and soluble interleukin-6 receptor (sIL6R) are elevated in primary open angle glaucoma (POAG). LPA and IL6 modulate in response to biomechanical stimuli and converge on similar fibrotic phenotypes. Thus, we determined whether LPA and IL6 trans-signaling (IL6/sIL6...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Invest Ophthalmol Vis Sci
मुख्य लेखकों: Yemanyi, Felix, Raghunathan, VijayKrishna
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Association for Research in Vision and Ophthalmology 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683860/
https://ncbi.nlm.nih.gov/pubmed/33216119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.13.29
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