Cargando...

Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells

PURPOSE: Lysophosphatidic acid (LPA), a bioactive lipid, has been shown to increase resistance to aqueous humor outflow (AH) through the trabecular meshwork (TM). The molecular basis for this response of the TM to LPA, however, is not completely understood. In this study, we explored the possible in...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Invest Ophthalmol Vis Sci
Main Authors: Ho, Leona T. Y., Skiba, Nikolai, Ullmer, Christoph, Rao, Ponugoti Vasantha
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5896423/
https://ncbi.nlm.nih.gov/pubmed/29677358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23702
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!