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Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells

PURPOSE: To explore the role of inducible focal adhesion (FA) protein Hic-5 in actin cytoskeletal reorganization, FA formation, fibrogenic activity, and expression of myocilin in trabecular meshwork (TM) cells. METHODS: Using primary cultures of human TM (HTM) cells, the effects of various external...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Pattabiraman, Padmanabhan Paranji, Rao, Ponugoti Vasantha
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553930/
https://ncbi.nlm.nih.gov/pubmed/26313302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17204
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