RhoA GTPase-Induced Ocular Hypertension in a Rodent Model Is Associated with Increased Fibrogenic Activity in the Trabecular Meshwork

Ocular hypertension arising from increased resistance to aqueous humor (AH) outflow through the trabecular meshwork is a primary risk factor for open-angle glaucoma, a leading cause of blindness. Ongoing efforts have found little about the molecular and cellular bases of increased resistance to AH o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Pathol
Main Authors: Pattabiraman, Padmanabhan P., Rinkoski, Tommy, Poeschla, Eric, Proia, Alan, Challa, Pratap, Rao, Ponugoti V.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2015
נושאים:
Regular Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305183/
https://ncbi.nlm.nih.gov/pubmed/25499974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.10.023
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