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Glucocorticoid-induced cell-derived matrix modulates transforming growth factor β2 signaling in human trabecular meshwork cells

Aberrant remodeling of trabecular meshwork (TM) extracellular matrix (ECM) may induce ocular hypertensive phenotypes in human TM (hTM) cells to cause ocular hypertension, via a yet unknown mechanism. Here, we show that, in the absence of exogenous transforming growth factor-beta2 (TGFβ2), compared w...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Yemanyi, Felix, Vranka, Janice, Raghunathan, Vijay Krishna
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518434/
https://ncbi.nlm.nih.gov/pubmed/32973273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72779-w
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