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Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype

PURPOSE: Wnt is a spatiotemporally regulated signaling pathway whose inhibition is associated with glaucoma, elevated intraocular pressure (IOP), and cell stiffening. Whether such changes are permanent or may be reversed is unclear. Here, we determine if activation of Wnt pathway after inhibition re...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Dhamodaran, Kamesh, Baidouri, Hasna, Sandoval, Lyndsey, Raghunathan, VijayKrishna
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415288/
https://ncbi.nlm.nih.gov/pubmed/32539133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.30
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