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The intrinsic stiffness of human trabecular meshwork cells increases with senescence

Dysfunction of the human trabecular meshwork (HTM) plays a central role in the age-associated disease glaucoma, a leading cause of irreversible blindness. The etiology remains poorly understood but cellular senescence, increased stiffness of the tissue, and the expression of Wnt antagonists such as...

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Publicat a:Oncotarget
Autors principals: Morgan, Joshua T., Raghunathan, Vijay Krishna, Chang, Yow-Ren, Murphy, Christopher J., Russell, Paul
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558157/
https://ncbi.nlm.nih.gov/pubmed/25915531
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