HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington’s disease (HD). While HD has been described primarily as a...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Mielcarek, Michal, Toczek, Marta, Smeets, Cleo J. L. M., Franklin, Sophie A., Bondulich, Marie K., Jolinon, Nelly, Muller, Thomas, Ahmed, Mhoriam, Dick, James R. T., Piotrowska, Izabela, Greensmith, Linda, Smolenski, Ryszard T., Bates, Gillian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352047/
https://ncbi.nlm.nih.gov/pubmed/25748626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005021
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