HDAC4-Myogenin Axis As an Important Marker of HD-Related Skeletal Muscle Atrophy

Skeletal muscle remodelling and contractile dysfunction occur through both acute and chronic disease processes. These include the accumulation of insoluble aggregates of misfolded amyloid proteins that is a pathological feature of Huntington’s disease (HD). While HD has been described primarily as a...

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Publicado en:PLoS Genet
Autores principales: Mielcarek, Michal, Toczek, Marta, Smeets, Cleo J. L. M., Franklin, Sophie A., Bondulich, Marie K., Jolinon, Nelly, Muller, Thomas, Ahmed, Mhoriam, Dick, James R. T., Piotrowska, Izabela, Greensmith, Linda, Smolenski, Ryszard T., Bates, Gillian P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352047/
https://ncbi.nlm.nih.gov/pubmed/25748626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005021
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