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The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model

Huntington's disease (HD) is neurodegenerative disorder for which the mutation results in an extra-long tract of glutamines that causes the huntingtin protein to aggregate. It is characterized by neurological symptoms and brain pathology that is associated with nuclear and cytoplasmic aggregate...

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Bibliografiske detaljer
Main Authors: Mielcarek, Michal, Bondulich, Marie K., Inuabasi, Linda, Franklin, Sophie A., Muller, Thomas, Bates, Gillian P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182603/
https://ncbi.nlm.nih.gov/pubmed/25268775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108961
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