Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

Maintenance of skeletal muscle structure and function requires innervation by motor neurons, such that denervation causes muscle atrophy. We show that myogenin, an essential regulator of muscle development, controls neurogenic atrophy. Myogenin is up-regulated in skeletal muscle following denervatio...

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Detalhes bibliográficos
Main Authors: Moresi, Viviana, Williams, Andrew H., Meadows, Eric, Flynn, Jesse M., Potthoff, Matthew J., McAnally, John, Shelton, John M., Backs, Johannes, Klein, William H., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982779/
https://ncbi.nlm.nih.gov/pubmed/20887891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.09.004
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