HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related to muscle atrophy, but the underlying mechani...

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Опубликовано в: :Front Cell Neurosci
Главные авторы: Ma, Wenjing, Cai, Yong, Shen, Yuntian, Chen, Xin, Zhang, Lilei, Ji, Yanan, Chen, Zehao, Zhu, Jianwei, Yang, Xiaoming, Sun, Hualin
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Cellular Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278478/
https://ncbi.nlm.nih.gov/pubmed/34276308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.663384
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