HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related to muscle atrophy, but the underlying mechani...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Ma, Wenjing, Cai, Yong, Shen, Yuntian, Chen, Xin, Zhang, Lilei, Ji, Yanan, Chen, Zehao, Zhu, Jianwei, Yang, Xiaoming, Sun, Hualin
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Cellular Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278478/
https://ncbi.nlm.nih.gov/pubmed/34276308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.663384
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