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A Novel Class of Bis- and Tris-Chelate Diam(m)inebis(dicarboxylato)platinum(IV) Complexes as Potential Anticancer Prodrugs
A novel class of platinum(IV) complexes of the type [Pt(Am)-(R(COO)(2))(2)], where Am is a chelating diamine or two monodentate am(m)ine ligands and R(COO)(2) is a chelating dicarboxylato moiety, was synthesized. For this purpose, the reaction between the corresponding tetrahydroxidoplatinum(IV) pre...
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| 出版年: | J Med Chem |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351917/ https://ncbi.nlm.nih.gov/pubmed/25032896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500791c |
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