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Mechanism of Microhomology-Mediated End-Joining Promoted by Human DNA Polymerase Theta
Microhomology-mediated end-joining (MMEJ) is an error-prone alternative double-strand break repair pathway that utilizes sequence microhomology to recombine broken DNA. Although MMEJ is implicated in cancer development, the mechanism of this pathway is unknown. We demonstrate that purified human DNA...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Struct Mol Biol |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351179/ https://ncbi.nlm.nih.gov/pubmed/25643323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2961 |
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