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DNA interstrand cross-link repair requires replication fork convergence
DNA interstrand cross-links (ICLs) prevent strand separation during DNA replication and transcription and are therefore extremely cytotoxic. In metazoans, a major pathway of ICL repair is coupled to DNA replication and requires the Fanconi anemia pathway. In most current models, collision of a singl...
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| Publié dans: | Nat Struct Mol Biol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351167/ https://ncbi.nlm.nih.gov/pubmed/25643322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2956 |
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