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Mechanism and regulation of incisions during DNA interstrand cross-link repair

A critical step in DNA interstrand cross-link repair is the programmed collapse of replication forks that have stalled at an ICL. This event is regulated by the Fanconi anemia pathway, which suppresses bone marrow failure and cancer. In this perspective, we focus on the structure of forks that have...

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Detalhes bibliográficos
Main Authors: Zhang, Jieqiong, Walter, Johannes C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076290/
https://ncbi.nlm.nih.gov/pubmed/24768452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.03.018
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