Lincosamide Synthetase—A Unique Condensation System Combining Elements of Nonribosomal Peptide Synthetase and Mycothiol Metabolism

In the biosynthesis of lincosamide antibiotics lincomycin and celesticetin, the amino acid and amino sugar units are linked by an amide bond. The respective condensing enzyme lincosamide synthetase (LS) is expected to be an unusual system combining nonribosomal peptide synthetase (NRPS) components w...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Janata, Jiri, Kadlcik, Stanislav, Koberska, Marketa, Ulanova, Dana, Kamenik, Zdenek, Novak, Petr, Kopecky, Jan, Novotna, Jitka, Radojevic, Bojana, Plhackova, Kamila, Gazak, Radek, Najmanova, Lucie
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351081/
https://ncbi.nlm.nih.gov/pubmed/25741696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118850
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