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Lincosamide Synthetase—A Unique Condensation System Combining Elements of Nonribosomal Peptide Synthetase and Mycothiol Metabolism

In the biosynthesis of lincosamide antibiotics lincomycin and celesticetin, the amino acid and amino sugar units are linked by an amide bond. The respective condensing enzyme lincosamide synthetase (LS) is expected to be an unusual system combining nonribosomal peptide synthetase (NRPS) components w...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Janata, Jiri, Kadlcik, Stanislav, Koberska, Marketa, Ulanova, Dana, Kamenik, Zdenek, Novak, Petr, Kopecky, Jan, Novotna, Jitka, Radojevic, Bojana, Plhackova, Kamila, Gazak, Radek, Najmanova, Lucie
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351081/
https://ncbi.nlm.nih.gov/pubmed/25741696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118850
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