GP130 activation induces myeloma and collaborates with MYC

Multiple myeloma (MM) is a plasma cell neoplasm that results from clonal expansion of an Ig-secreting terminally differentiated B cell. Advanced MM is characterized by tissue damage that involves bone, kidney, and other organs and is typically associated with recurrent genetic abnormalities. IL-6 si...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Dechow, Tobias, Steidle, Sabine, Götze, Katharina S., Rudelius, Martina, Behnke, Kerstin, Pechloff, Konstanze, Kratzat, Susanne, Bullinger, Lars, Fend, Falko, Soberon, Valeria, Mitova, Nadya, Li, Zhoulei, Thaler, Markus, Bauer, Jan, Pietschmann, Elke, Albers, Corinna, Grundler, Rebekka, Schmidt-Supprian, Marc, Ruland, Jürgen, Peschel, Christian, Duyster, Justus, Rose-John, Stefan, Bassermann, Florian, Keller, Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348946/
https://ncbi.nlm.nih.gov/pubmed/25384216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69094
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