Retroviral insertional mutagenesis identifies RUNX genes involved in chronic myeloid leukemia disease persistence under imatinib treatment

The kinase inhibitor imatinib mesylate targeting the oncoprotein Bcr-Abl has revolutionized the treatment of chronic myeloid leukemia (CML). However, even though imatinib successfully controls the leukemia in chronic phase, it seems not to be able to cure the disease, potentially necessitating lifel...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Miething, Cornelius, Grundler, Rebekka, Mugler, Claudia, Brero, Simone, Hoepfl, Josef, Geigl, Jochen, Speicher, Michael R., Ottmann, Oliver, Peschel, Christian, Duyster, Justus
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810334/
https://ncbi.nlm.nih.gov/pubmed/17360569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604716104
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