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Detecting Statistically Significant Common Insertion Sites in Retroviral Insertional Mutagenesis Screens

Retroviral insertional mutagenesis screens, which identify genes involved in tumor development in mice, have yielded a substantial number of retroviral integration sites, and this number is expected to grow substantially due to the introduction of high-throughput screening techniques. The data of va...

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Autori principali: de Ridder, Jeroen, Uren, Anthony, Kool, Jaap, Reinders, Marcel, Wessels, Lodewyk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676030/
https://ncbi.nlm.nih.gov/pubmed/17154714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0020166
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