GP130 activation induces myeloma and collaborates with MYC

Multiple myeloma (MM) is a plasma cell neoplasm that results from clonal expansion of an Ig-secreting terminally differentiated B cell. Advanced MM is characterized by tissue damage that involves bone, kidney, and other organs and is typically associated with recurrent genetic abnormalities. IL-6 si...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dechow, Tobias, Steidle, Sabine, Götze, Katharina S., Rudelius, Martina, Behnke, Kerstin, Pechloff, Konstanze, Kratzat, Susanne, Bullinger, Lars, Fend, Falko, Soberon, Valeria, Mitova, Nadya, Li, Zhoulei, Thaler, Markus, Bauer, Jan, Pietschmann, Elke, Albers, Corinna, Grundler, Rebekka, Schmidt-Supprian, Marc, Ruland, Jürgen, Peschel, Christian, Duyster, Justus, Rose-John, Stefan, Bassermann, Florian, Keller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348946/
https://ncbi.nlm.nih.gov/pubmed/25384216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69094
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