GP130 activation induces myeloma and collaborates with MYC

Multiple myeloma (MM) is a plasma cell neoplasm that results from clonal expansion of an Ig-secreting terminally differentiated B cell. Advanced MM is characterized by tissue damage that involves bone, kidney, and other organs and is typically associated with recurrent genetic abnormalities. IL-6 si...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Dechow, Tobias, Steidle, Sabine, Götze, Katharina S., Rudelius, Martina, Behnke, Kerstin, Pechloff, Konstanze, Kratzat, Susanne, Bullinger, Lars, Fend, Falko, Soberon, Valeria, Mitova, Nadya, Li, Zhoulei, Thaler, Markus, Bauer, Jan, Pietschmann, Elke, Albers, Corinna, Grundler, Rebekka, Schmidt-Supprian, Marc, Ruland, Jürgen, Peschel, Christian, Duyster, Justus, Rose-John, Stefan, Bassermann, Florian, Keller, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348946/
https://ncbi.nlm.nih.gov/pubmed/25384216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69094
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