Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-x(L) strategies through Mcl-1 down-regulation

Ovarian carcinoma is the leading cause of death from gynecologic cancer in the developed world and is characterized by acquired chemoresistance leading to an overall 5-year survival rate of about 30 %. We previously showed that Bcl-x(L) and Mcl-1 cooperatively protect platinum-resistant ovarian canc...

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Опубликовано в: :Apoptosis
Главные авторы: Bonnefond, Marie-Laure, Lambert, Bernard, Giffard, Florence, Abeilard, Edwige, Brotin, Emilie, Louis, Marie-Hélène, Gueye, Mor Sény, Gauduchon, Pascal, Poulain, Laurent, N’Diaye, Monique
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2015
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348506/
https://ncbi.nlm.nih.gov/pubmed/25627260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1095-3
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