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Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-x(L) strategies through Mcl-1 down-regulation
Ovarian carcinoma is the leading cause of death from gynecologic cancer in the developed world and is characterized by acquired chemoresistance leading to an overall 5-year survival rate of about 30 %. We previously showed that Bcl-x(L) and Mcl-1 cooperatively protect platinum-resistant ovarian canc...
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| Izdano u: | Apoptosis |
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| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer US
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348506/ https://ncbi.nlm.nih.gov/pubmed/25627260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1095-3 |
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