DNA Methyl Transferase 1 Reduces Expression of SRD5A2 in the Aging Adult Prostate

5-α Reductase type 2 (SRD5A2) is a critical enzyme for prostatic development and growth. Inhibition of SRD5A2 by finasteride is used commonly for the management of urinary obstruction caused by benign prostatic hyperplasia. Contrary to common belief, we have found that expression of SRD5A2 is variab...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Ge, Rongbin, Wang, Zongwei, Bechis, Seth K., Otsetov, Alexander G., Hua, Shengyu, Wu, Shulin, Wu, Chin-Lee, Tabatabaei, Shahin, Olumi, Aria F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2015
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348471/
https://ncbi.nlm.nih.gov/pubmed/25700986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.11.020
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