DNA Methyl Transferase 1 Reduces Expression of SRD5A2 in the Aging Adult Prostate

5-α Reductase type 2 (SRD5A2) is a critical enzyme for prostatic development and growth. Inhibition of SRD5A2 by finasteride is used commonly for the management of urinary obstruction caused by benign prostatic hyperplasia. Contrary to common belief, we have found that expression of SRD5A2 is variab...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Ge, Rongbin, Wang, Zongwei, Bechis, Seth K., Otsetov, Alexander G., Hua, Shengyu, Wu, Shulin, Wu, Chin-Lee, Tabatabaei, Shahin, Olumi, Aria F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348471/
https://ncbi.nlm.nih.gov/pubmed/25700986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.11.020
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