Androgenic to oestrogenic switch in the human adult prostate gland is regulated by epigenetic silencing of steroid 5α-reductase 2

Benign prostatic hyperplasia is the most common proliferative abnormality of the prostate. All men experience some prostatic growth as they age, but the rate of growth varies among individuals. Steroid 5α-reductase 2 (SRD5A2) is a critical enzyme for prostatic development and growth. Previous work i...

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Veröffentlicht in:J Pathol
Hauptverfasser: Wang, Zongwei, Hu, Libing, Salari, Keyan, Bechis, Seth K, Ge, Rongbin, Wu, Shulin, Rassoulian, Cyrus, Pham, Jonathan, Wu, Chin-Lee, Tabatabaei, Shahin, Strand, Douglas W, Olumi, Aria F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212292/
https://ncbi.nlm.nih.gov/pubmed/28940538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4985
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