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Obesity-associated inflammation induces androgenic to estrogenic switch in the prostate gland
BACKGROUND & OBJECTIVE: Our patient cohort revealed that obesity is strongly associated with steroid-5α reductase type 2 (SRD5A2) promoter methylation and reduced protein expression. The underlying mechanism of prostatic growth in this population is poorly understood. Here we addressed the quest...
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| Publicat a: | Prostate Cancer Prostatic Dis |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7938647/ https://ncbi.nlm.nih.gov/pubmed/32029929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-020-0208-4 |
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