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Adenoviral-E2F-1 Radiosensitizes p53(wild-type) and p53(null) Human Prostate Cancer Cells

PURPOSE: E2F-1 is a transcription factor that enhances the radiosensitivity of various cell lines by inducing apoptosis. However, there are conflicting data concerning whether this enhancement is mediated via p53 dependent pathways. Additionally, the role of E2F-1 in the response of human prostate c...

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Dettagli Bibliografici
Pubblicato in:Int J Radiat Oncol Biol Phys
Autori principali: Nguyen, Khanh H., Hachem, Paul, Khor, Li-Yan, Salem, Naji, Hunt, Kelly K., Calkins, Peter R., Pollack, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347813/
https://ncbi.nlm.nih.gov/pubmed/15993550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2005.04.033
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