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ADENOVIRAL E2F1 OVEREXPRESSION SENSITIZES LNCAP AND PC3 PROSTATE TUMOR CELLS TO RADIATION IN VIVO
PURPOSE: We previously showed that E2F1 overexpression radiosensitizes prostate cancer cells in-vitro. Here, we demonstrate the radiosensitization efficacy of Ad-E2F1 in growing LNCaP (orthotopically) and PC3 (subcutaneously) nude mice xenograft tumors. METHODS AND MATERIALS: Adenoviral E2F1 was inj...
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| Veröffentlicht in: | Int J Radiat Oncol Biol Phys |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4299462/ https://ncbi.nlm.nih.gov/pubmed/21195876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.08.013 |
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