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Adenoviral-E2F-1 Radiosensitizes p53(wild-type) and p53(null) Human Prostate Cancer Cells

PURPOSE: E2F-1 is a transcription factor that enhances the radiosensitivity of various cell lines by inducing apoptosis. However, there are conflicting data concerning whether this enhancement is mediated via p53 dependent pathways. Additionally, the role of E2F-1 in the response of human prostate c...

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Detalhes bibliográficos
Publicado no:Int J Radiat Oncol Biol Phys
Main Authors: Nguyen, Khanh H., Hachem, Paul, Khor, Li-Yan, Salem, Naji, Hunt, Kelly K., Calkins, Peter R., Pollack, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347813/
https://ncbi.nlm.nih.gov/pubmed/15993550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2005.04.033
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